Located in Cologne, Germany, ADDPLAN GmbH is a privately held software company.

ADDPLAN GmbH was founded in 2002 by Gernot Wassmer and Reinhard Eisebitt as a result of their collaboration with the aim to apply the theory of adaptive study design to clinical research. The software package 'ADDPLAN Adaptive Designs - Plans and Analyses' started as a loose collection of programmes for adaptive sample size calculation, which later were transformed uniformly into object oriented programming language and complemented by further modules for the simulation and analysis of adaptive trials.

In order to profit from adaptive study design with all its wealth of flexibility one requires a user friendly and intuitive software package. Complicated conditional error calculations, power simulations and numerous planning options - made up of the experience from more than 30 adaptive trials that have been performed in the clinical phases II, III, and IV for many pharmaceutical companies, 'ADDPLAN Adaptive Designs - Plans and Analyses' was designed exactly for that purpose: 'ADDPLAN Adaptive Designs - Plans and Analyses' gives help and orientation to biostatisticians and clinical researchers in the evolving field of adaptive study design.